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Dr.
Yalcin Yavas,
Ph.D., HCLD, ELD, Laboratory Director.
Dr.
Yavas is certified as High-complexity
Clinical Laboratory Director (HCLD) and Embryology
Laboratory Director (ELD) by the American
Board of Bioanalysis (ABB). He is also licensed as
Clinical Laboratory Director by the State of Florida both in embryology and
andrology. Dr. Yavas received his Master of Science (M.S.)
degree from Washington
State University, Pullman, Washington, and his doctorate (Ph.D.) degree from University
of Guelph, Ontario, Canada, both in reproductive biology. Upon
completion of his Ph.D. degree, he acquired several years of extensive
experience in all aspects of Assisted Reproductive
Technologies (A.R.T.), including
micromanipulation. Dr. Yavas has particular expertise in intracytoplasmic sperm injection
(ICSI),
and has published many articles in scientific
journals. Dr. Yavas is a member of the American
Society for Reproductive Medicine (ASRM), the American
Association of Bioanalysts (AAB), the College
of Reproductive Biology, and the Canadian
Fertility and Andrology Society (CFAS).
Dr. Yavas is also the designer and developer
of our web site, and he maintains and updates it on a regular basis. You may send an e-mail to Dr. Yavas at DrYavas@yahoo.com
Education
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Ph.D. January 1997: Reproductive
Physiology, Department of Animal
and Poultry Science, University
of Guelph, Guelph,
Ontario,
Canada.
Major Professor:
Dr.
John S. Walton.
M.S. May 1992: Reproductive
Physiology, Department
of Animal Sciences, Washington
State University, Pullman,
Washington, U.S.A. Major Professor: Dr.
Jerry J. Reeves.
Please click on titles to read the abstracts.
Articles in Scientific Journals
-
2008
Yavas, Y., and
Selub, M.R. Ovarian follicular volume and follicular surface area are
better indicators of follicular growth and maturation, respectively, than is
follicular diameter. Fertil.
Steril.
(Alternate Link)
-
2004
Yavas, Y., and
Selub, M.R.
Intrauterine insemination (IUI) pregnancy outcome is
enhanced by shorter intervals from semen collection to sperm wash, from
sperm wash to IUI time, and from semen collection to IUI time.
82(6):1638-1647.
Fertil.
Steril.
(Alternate Link)
(Alternate
Link)
-
2001 Khamsi, F., Roberge, S.,
Yavas, Y., Lacanna,
I.C., Zhu, X., and Wong, J. Recent discoveries in physiology of insulin-like
growth factor-I and its interaction with gonadotropins in folliculogenesis.
16(3):151-165.
Endocrine.
(Alternate
Link)
-
2001
Yavas, Y.,
Roberge, S., Khamsi, F., Shirazi,
P., Endman, M.W., and Wong, J.C. Performing ICSI using an injection pipette
with the smallest possible inner diameter and a long taper increases normal
fertilization rate, decreases incidence of degeneration and tripronuclear
zygotes, and enhances embryo development. 18(8):426-435.
J.
Assist. Reprod. Genet.
(Alternate
Link)
-
2001
Khamsi, F., Yavas, Y., Roberge, S., Wong, J.C., Lacanna, I.C., and
Endman, M. Intracytoplasmic sperm injection increased fertilization and
good-quality embryo formation in patients with non-male factor indications
for in vitro fertilization: a prospective randomized study. 75(2):342-347.
Fertil.
Steril.
(Alternate
Link)
(Alternate
Link)
-
2001
Khamsi, F., Yavas, Y., Lacanna, I.C., Roberge, S., Endman, M., and
Wong, J.C. Exposure of human oocytes to endometrioma fluid does not alter
fertilization or early embryo development. 18(2):106-109.
J.
Assist. Reprod. Genet.
(Alternate
Link)
-
2000
Khamsi, F., Yavas, Y., Roberge, S., Lacanna, I.C., Wong, J.C., and
Endman, M. The status of controlled prospective clinical trials for efficacy
of intracytoplasmic sperm injection in in vitro fertilization for non-male
factor infertility. 17(9):504-507.
J.
Assist. Reprod. Genet.
(Alternate
Link)
-
2000
Yavas, Y., de Avila, D.M., and Reeves, J.J. Effectiveness of
norgestomet implants in suppressing ovulation and estrus in heifers varies
with stage of estrous cycle when implanted. 80(4):729-732.
Can.
J. Anim. Sci.
-
2000
Yavas, Y., and Walton, J.S. Induction of ovulation in postpartum
suckled beef cows. A Review. 54(1):1-23.
Theriogenology.
(Alternate
Link)
-
2000
Yavas, Y., and Walton, J.S. Postpartum acyclicity in suckled beef
cows. A Review. 54(1):25-55.
Theriogenology.
(Alternate
Link)
-
1999
Yavas, Y., Johnson, W.H., and Walton, J.S. Modification of follicular
dynamics by exogenous FSH and progesterone, and the induction of ovulation
using hCG in postpartum beef cows. 52(6):949-963.
Theriogenology.
(Alternate
Link)
-
1999
Khamsi, F., Roberge, S., Lacanna, I.C., Wong, J., and Yavas, Y.
Effects of granulosa cells, cumulus cells, and oocyte density on in vitro
fertilization in women. 10(2):161-166.
Endocrine.
-
1999
Khamsi, F., Roberge, S., Yavas, Y., Lacanna, I.C., The, B.L., Wong,
J., and Endman, M. In vitro fertilization and intra-cytoplasmic sperm
injection into the oocyte at Toronto Fertility Sterility Institute (14-year
evolution of an independent health facility). 32(2):82-86. Annals of The Royal College of
Physicians and Surgeons of Canada.
-
1996
Yavas, Y., de Avila, D.M., and Reeves, J.J. Trucking stress at
breeding does not lower conception rate of beef heifers. 45(3):623-632.
Theriogenology.
Letter
1999
Yavas, Y., and Roberge, S. ICSI Technique - Impact on Fertilization Rate.
71(6):1165. Fertil.
Steril.
Abstracts
-
2006
Yavas, Y., and
Selub, M.R. Ovarian follicular volume and follicular surface area are more
accurate indicators of follicular growth and maturation, respectively, than
follicular diameter alone. 86(Suppl.2):S398-S399
(abstr.P-715). Fertil.
Steril.
-
2005 Yavas, Y., and
Selub, M.R.
Incubating washed spermatozoa at 37OC rather than keeping at room
temperature (20OC) until intrauterine insemination (IUI) time
results in higher pregnancy rate. 84(Suppl.1):S265-S266
(abstr.P-322). Fertil.
Steril.
-
2004 Yavas, Y., Selub, M.R.,
and Carmichael, D. The adverse effect of female age on intra-uterine
insemination (IUI) pregnancy outcome is more pronounced within donor
frozen-thawed sperm IUI cycles than within partner’s fresh sperm IUI
cycles regardless of stimulation type. 82(Suppl.2):S218 (abstr.P-235). Fertil.
Steril.
-
2003 Yavas, Y., Selub, M.R.,
Lefkow, H., and Carmichael, D. Intra-uterine insemination (IUI) outcome is
enhanced by shorter intervals from semen collection to sperm wash, from
sperm wash to IUI time, and from semen collection to IUI time. 80(Suppl.3):S152(abstr.P-97). Fertil.
Steril.
-
2003 Yavas, Y., Selub, M.R.,
Lefkow, H., and Carmichael, D. Type of donor frozen sperm does not affect
intra-uterine insemination (IUI) outcome. 80(Suppl.3):S168(abstr.P-139). Fertil.
Steril.
-
2003 Yavas, Y., Selub, M.R.,
Lefkow, H., and Carmichael, D. Ovarian stimulation with human menopausal
gonadotropin (hMG) is more effective than clomiphene citrate (CC) in
intra-uterine insemination (IUI) using partner’s sperm, but not in IUI
using donor frozen sperm. 80(Suppl.3):S168(abstr.P-141). Fertil.
Steril.
-
2000
Khamsi, F., Yavas, Y., Roberge, S., Lacanna, I.C., Wong, J.C., and
Endman, M. Mural granulosa cells (as opposed to
cumulus oophorus) may produce a factor inhibiting oocyte fertilization and
early embryo development in human. 46th Annual Meeting (abstr.TP21). Canadian
Fertility and Andrology Society.
-
2000 Khamsi, F., Yavas, Y., Lacanna, I.C., Roberge, S., Endman, M., and Wong, J.C. Exposure of human
oocytes to endometrioma fluid does not alter fertilization or early embryo
development. 46th Annual Meeting (abstr.FP14).
Canadian
Fertility and Andrology Society.
-
2000 Lacanna, I.C., Khamsi, F., Yavas,
Y., Roberge, S., Wong, J.C., The, B.L., and Endman, M. Intracytoplasmic
sperm injection increased fertilization and good-quality embryo formation in
patients with non-male indications for in vitro fertilization. A prospective
randomized study. 46th Annual Meeting (abstr.FP15).
Canadian
Fertility and Andrology Society.
-
2000 Khamsi, F., Afzal, D.N., The,
L., Wong, J., Yavas, Y., and Endman, M. Increasing number of embryos
transferred increases pregnancy rate in IVF cycles. 46th Annual Meeting
(abstr.FP19). Canadian
Fertility and Andrology Society.
-
1999 Roberge, S., Yavas, Y., Nicot-Montalvo, L., Gopalasundaram, K.,
Endman, M., and Khamsi, F. Increased
DNA synthesis in oocyte-cumulus complexes (OCCs) of rats treated in vivo
with an insulin-like growth factor-I (IGF-I) analogue. Suppl. p.S229.
(abstr.P-431). Fertil.
Steril.
-
1998 Yavas, Y., Roberge,
S., Lacanna, I., Wong, J., Khamsi, F., and Endman, M. Factors that may
influence pregnancy rate in an intracytoplasmic sperm injection (ICSI)
program. 44th Annual Meeting (abstr.TP5). Canadian
Fertility and Andrology Society.
-
1998 Yavas, Y., Roberge,
S., Lacanna, I., Khamsi, F., and Wong, J. Simplification of IVF. 6. The type
of syringe used for oocyte aspiration. 44th Annual Meeting (abstr.FP4). Canadian
Fertility and Andrology Society.
-
1998 Roberge, S., Yavas, Y.,
Shirazi, P., Lacanna, I., Wong, J., and Khamsi, F. Simplification of IVF. 7.
Comparison of human serum albumin purchased commercially versus patient's
own serum and comparison of commercially purchased culture medium versus
culture medium produced on site. 44th Annual Meeting (abstr.FP5). Canadian
Fertility and Andrology Society.
-
1998 Roberge, S., Yavas, Y.,
Shirazi, P., and Khamsi, F. Effect of ovarian stimulation type on pregnancy
outcome in therapeutic donor insemination program. 44th Annual Meeting
(abstr.FP21). Canadian
Fertility and Andrology Society.
-
1997 Khamsi, F., Roberge, S.,
Rouleau, A., Yavas, Y., and Armstrong, D.T.
In vivo infusion with IGF-I analogue, long arg3-insulin-like growth factor-I
(LR3-IGF-I), enhances superovulatory response in rats. Suppl.
p.S88-S89. (abstr.40). Fertil.
Steril.
-
1997 Yavas, Y., Roberge,
S., Shirazi, P., Agrawal, A., Llano, M., Wong, J., Lacanna, I., and Khamsi,
F. Effects of sperm motility survival rate on fertilization rate in IVF
program. 43rd Annual Meeting (abstr.FP33). Canadian
Fertility and Andrology Society.
-
1997 Roberge, S., Yavas, Y.,
Wong, J., Lacanna, I., and Khamsi, F. Effects of different ovarian
stimulation protocols for IVF on cumulus size, estradiol peak and
fertilization rate. 43rd Annual Meeting (abstr.TP13). Canadian
Fertility and Andrology Society.
-
1997 Roberge, S., Rouleau, A., Yavas,
Y., Armstrong, D.T., and Khamsi, F. Increased ovarian stimulation of
rats infused with IGF-I analogue, long arg3-insulin-like growth factor-I
(LR3-IGF-I). 43rd Annual Meeting (abstr.FP8). Canadian
Fertility and Andrology Society.
-
1997 Roberge, S., Yavas, Y.,
Wong, J., Lacanna, I., and Khamsi, F. Cost effectiveness of seeking
accreditation of a reproductive laboratory by the College of American
Pathologists. 43rd Annual Meeting (abstr.FP32). Canadian
Fertility and Andrology Society.
-
1995 Yavas, Y., Roberge,
S., Buhr, M.M., Johnson, W., Liptrap, R.M., and Walton, J.S. Effect of
gonadotropins and progesterone on follicular dynamics and ovulation in
postpartum beef cows. 73(Suppl.1):231(abstr.485). J.
Anim. Sci.
-
1994 Yavas, Y., Roberge,
S., Buhr, M.M., Johnson, W., Liptrap, R.M., and Walton, J.S. Effects of FSH,
bST and progesterone on follicular dynamics in postpartum suckled beef cows.
50(Suppl.1):64(abstr.40). Biol.
Reprod.
-
1992 Yavas, Y., and Reeves,
J.J. Stress at breeding does not lower conception rates of heifers. 70(Suppl.1):254(abstr.466).
J. Anim. Sci.
Presentations
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2006 Yavas, Y.,
and Selub, M.R. Ovarian follicular volume and follicular surface area are
more accurate indicators of follicular growth and maturation, respectively,
than follicular diameter alone. 62nd Annual Meeting of the American
Society for Reproductive Medicine. October 23-25. New Orleans, Louisiana (poster).
-
2005 Yavas, Y., and Selub, M.R.
Incubating washed spermatozoa at 37OC rather than keeping at room
temperature (20OC) until intrauterine insemination (IUI) time
results in higher pregnancy rate. 61st Annual Meeting of the American
Society for Reproductive Medicine. October 17-19. Montreal, Canada (poster).
-
2004 Yavas, Y., Selub, M.R.,
and Carmichael, D. The adverse effect of female age on intra-uterine
insemination (IUI) pregnancy outcome is more pronounced within donor
frozen-thawed sperm IUI cycles than within partner’s fresh sperm IUI
cycles regardless of stimulation type. 60th Annual
Meeting of the American
Society for Reproductive Medicine. October 18-20. Philadelphia, Pennsylvania
(poster).
-
2003 Yavas, Y., Selub, M.R.,
Lefkow, H., and Carmichael, D. Intra-uterine insemination (IUI) outcome is
enhanced by shorter intervals from semen collection to sperm wash, from
sperm wash to IUI time, and from semen collection to IUI time. 59th Annual
Meeting of the American
Society for Reproductive Medicine. October 13-15. San Antonio, Texas
(poster).
-
2003 Yavas, Y., Selub, M.R.,
Lefkow, H., and Carmichael, D. Ovarian stimulation with human menopausal
gonadotropin (hMG) is more effective than clomiphene citrate (CC) in
intra-uterine insemination (IUI) using partner’s sperm, but not in IUI
using donor frozen sperm. 59th Annual Meeting of the American
Society for Reproductive Medicine. October 13-15. San Antonio, Texas
(poster).
-
2003 Yavas, Y., Selub, M.R.,
Lefkow, H., and Carmichael, D. Type of donor frozen sperm does not affect
intra-uterine insemination (IUI) outcome. 59th Annual Meeting of the American
Society for Reproductive Medicine. October 13-15. San Antonio, Texas
(poster).
-
1998 Yavas, Y., Roberge, S.,
Lacanna, I., Wong,
J., Khamsi, F., and Endman, M. Factors that may influence pregnancy rate in
an intracytoplasmic sperm injection. 44th Annual Meeting of the Canadian
Fertility and Andrology Society. September 9-12. Mont-Tremblant,
Quebec, Canada (poster).
-
1998 Yavas, Y., Roberge,
S., Lacanna, I., Khamsi, F., and Wong, J. Simplification of IVF. 6. The type
of syringe used for oocyte aspiration. 44th Annual Meeting of the Canadian
Fertility and Andrology Society. September 9-12. Mont-Tremblant,
Quebec, Canada (poster).
-
1995 Yavas, Y., Roberge,
S., Buhr, M.M., Johnson, W., Liptrap, R.M., and Walton, J.S. Effect of
gonadotropins and progesterone on follicular dynamics and ovulation in
postpartum beef cows. 87th Annual Meeting of the American
Society of Animal Science. July 27. Orlando, Florida (slide).
-
1994 Yavas, Y., Roberge,
S., Buhr, M.M., Johnson, W., Liptrap, R.M., and Walton, J.S. Effects of FSH,
bST and progesterone on follicular dynamics in postpartum suckled beef cows.
27th Annual Meeting of the Society
for the Study of Reproduction. July 24-27. Ann Arbor, Michigan
(poster).
-
1992 Yavas, Y., and Reeves,
J.J. Stress at breeding does not lower conception rates of heifers. 84th
Annual Meeting of the American
Society of Animal Science. August 10. Pittsburgh, Pennsylvania (slide).
Scientific Meetings Attended - Continuing Education
2006
American Society for Reproductive Medicine 62nd Annual Meeting. October
23-25. New Orleans, Louisiana.
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2005 American
Society for Reproductive Medicine 61st
Annual Meeting. October 17-19. Montreal, Canada.
2004 American
Society for Reproductive Medicine 60th
Annual Meeting. October 18-20. Philadelphia, Pennsylvania.
2003 American
Society for Reproductive Medicine 59th
Annual Meeting. October 13-15. San Antonio, Texas.
2003 American
Society for Reproductive Medicine Post-graduate Course: Good to Great: A
Detailed Analysis of IVF Laboratory Techniques to Improve Outcomes. October
12. San Antonio, Texas.
2001 American
Society for Reproductive Medicine 57th
Annual Meeting. October 22-25. Orlando, Florida.
2001 American
Society for Reproductive Medicine Post-graduate Course: Molecular,
Developmental, and Reproductive Biology of Gametes and Embryos: Basic
Concepts and Clinical Applications. October 20-21. Orlando, Florida.
1999 Conjoint Annual Meeting of American
Society for Reproductive Medicine and Canadian
Fertility and Andrology Society. September 27-30. Toronto, Ontario,
Canada.
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1999 American
Society for Reproductive Medicine Post-graduate Course: Taking ART to
Year 2000: Theories and Solutions for Current Laboratory Practices. September
25-26. Toronto, Ontario, Canada.
1999 American
Association of Bioanalysts, College
of Reproductive Biology Annual Meeting and Educational Conference.
May 20-21. San Diego, California.
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1998 Canadian
Fertility and Andrology Society 44th Annual Meeting. September 9-12.
Mont-Tremblant, Quebec, Canada.
1995 American
Society of Animal Science 87th Annual Meeting. July 27. Orlando, Florida.
1994 Society
for the Study of Reproduction 27th Annual Meeting. July 24-27. Ann
Arbor, Michigan.
1992 American
Society of Animal Science 84th Annual Meeting. August 10. Pittsburgh,
Pennsylvania.
1991 American
Society of Animal Science 83rd Annual Meeting. Reno, Nevada.
1990 American
Society of Animal Science 82nd Annual Meeting. Bozeman, Montana.
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