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Instructions for Taking MedicationsInstructions for Daily Lupron Injections Instructions for Gonadotropin Injections Sites for Subcutaneous Injections of Daily Lupron and Gonadotropin Instructions for Profasi (hCG) Injection Instructions for Crinone Vaginal Gel Application Instructions for *Daily Lupron InjectionsLupron comes in 2 or 4 week kits which includes a vial of liquid medication and special small syringes for injection just under the skin. This medication is started approximately 1 week before an expected menstrual period, or any time in your cycle if your physician gives you birth control pills to prepare your ovaries for the Lupron injections. We prefer that you take the injections in the morning. Try to take it at the same time each day. Vaginal bleeding usually starts several days after starting the medication. We will give you specific instructions regarding your dose of Lupron and how long to stay on the medication. Call our office if vaginal bleeding does not start after 10 days of starting Lupron. If you will be decreasing your dose, call our office if vaginal bleeding does not start before the decrease. (*Some patients may use a long-acting, depot form of Lupron. This medication is given as a single, intramuscular injection.) Summary for Lupron Injection1. Wash top of bottle with alcohol pad 2. Draw up 0.20 cc of air in syringe 3. Put needle in bottle 4. Push in the air and draw out 0.20 cc of medication 5. Put cap back on syringe 6. Decide where to inject 7. Wash skin with alcohol pad 8. Pinch up skin 9. Put needle into skin 10. Pull back on plunger 11. Push in medication 12. Take needle out Call the office (1 . 954 . 217 . 3456 ) if any questions about the medication arise. Report increasing local pain or redness at injection sites. Remember that hot flashes are an expected potential side effect. Protocol for Suppression Therapy with LupronMedication: Lupron (bottle of 2.8 cc) Injection Equipment: Tuberculin syringes with attached needles for subcutaneous injection. Make sure to use a new syringe and needle for every injection. Alcohol pads. Injection Site: Inject Lupron subcutaneously. Optimal sites are thigh and lower abdominal wall. Lift up skin flap between thumb and index finger. Inject parallel to skin level. Dosage for suppression: 0.1 cc or 0.2 cc of Lupron every morning starting approximately cycle day 21 and continuing for a total of ten days. If you were not started on Lupron on cycle day 21 but prescribed Norlutate or oral contraceptive (OC) tablets, please start injection of Lupron on the fourth day of Norlutate or therapy (unless instructed otherwise by us) and continue for a total of ten days. Make appointment for your next visit. Dosage During Stimulation: Stop medication or 0.1 cc of Lupron every morning from day 1 of stimulation through the day of hCG. Important Recommendations:a. Draw up your medication while sitting at a table, allow for adequate space and time to make these preparations. This will prevent spillage, waste of medication, or contamination of needles. b. If you are unable to dispose of the needless and syringes properly, recap the needle, leave it on the syringe, place it in a Ziploc bag and return it to our office during your next visit. We will assure proper disposal. c. Keep medication refrigerated or at room temperature. Do not leave in your hot car during the day when you are at work. Store all needles and syringes outside the reach of children. d. Please contact us if in doubt about any of the above steps, or if you have other questions, at 1 . 954 . 217 . 3456 . Instructions for Gonadotropin InjectionsFor Intramuscular Injections (Pergonal, Humegon, Repronex or Metrodin):Use ½ cc of liquid to dilute each ampule of powder medication you are going to use. After opening all the ampules you will use, draw up the liquid (1, 1½, or 2 cc) into your syringe. Squirt the liquid into the ampule containing the powder, then draw the mixture back into the syringe. Repeat this process using the same syringe and the same liquid until all powders have been mixed with the liquid in the syringe. The mixture must be injected deep into the muscle of the buttock. Do not be concerned if you see a little blood on the skin after the injection or if some fluid leaks out of the injection site. You must use a 1½ inch needle to be sure the medication is injected deeply (past the fat). For Subcutaneous Injections (Fertinex, Repronex, Follistim, or Gonal-F):For your total number of ampules, you will need to use between ½ and 1 cc of liquid to dilute the powders. After opening all of the ampules you will need, draw up the liquid into the syringe. Squirt the liquid into the ampule containing the powder, then draw the mixture back into the syringe. Repeat this process using the same syringe and the same liquid until all powders have been mixed with the liquid in the syringe. The injection must be administered just into the fatty tissue, under the skin (upper arm, abdomen or thigh). Do not be concerned if you see a little blood on the skin after the injection or if some fluid leaks out of the injection site. You must use a ½ or ⅝ inch needle. Step-by-step Instructions for Repronex InjectionsPlease click on images.
Sites for Subcutaneous Injections of Daily Lupron and Gonadotropin
Instructions for Profasi (hCG) Injection(Sometimes known as Pregnyl) Profasi or “hCG” (Human Chorionic Gonadotropin 10,000 Unit) is taken when your follicles and the eggs they contain are determined to be mature. We will inform you of the exact time you will need to inject the hCG. You will usually only need one injection of this medication. It is extremely important that you follow these directions and administer the injection at the time you are instructed to do so. The hCG comes in powder form with another vial containing the liquid diluent. You will need to mix 2 cc of the diluent with all of the powder in the hCG bottle. When powder is dissolved, draw the contents into the syringe and inject it deep into the muscle. A few patients will be instructed not to inject the entire 2 cc. PLEASE, be sure you know the exact time at which to take the medication, and follow all instructions carefully. Instructions for Crinone Vaginal Gel ApplicationCrinone vaginal gel is the hormone Progesterone, in gel form, for absorption through the vaginal wall. Progesterone promotes implantation. Application of the gel is to begin the day of your egg retrieval. The dose will increase on the third day. The gel is to be inserted vaginally and will be absorbed through the vaginal wall. Do not become alarmed if you notice some of the gel leaking from the vagina. Sufficient medication will still be absorbed.
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